東京大学大学院新領域創成科学研究科 青木不学先生、那順布和先生、湯川将之先生 (2009) B6D2F1の受精卵にマイクロインジェクションして作成。C57BL/6と交配を行い維持。 CAG promoter (CMV-IE enhancer, chicken beta-actin promoter, rabbit beta-globin genomic DNA), Flag-tag cDNA, Mouse Histone H2A.Z (H2afz) gene cDNA C(3〜6か月) B6-Flag/H2A.Z Tg B6-Flag/H2A.Z Tg 条件を付加しない。 戻し交配系統名 (ブリーダー名) : C57BL/6 (日本SLC) Necessary documents for ordering:<ol><li>Order form (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_4.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_b.docx">English</A>)</li><li>Category I MTA: MTA for distribution with RIKEN BRC (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_5.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_c.docx">English</A>)</li><li>CAGGS MTA (<A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/CAGGS_MTA.docx">English</A>)</li><li>Acceptance of responsibility for living modified organism (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_7.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_g.docx">English</A>)</li></ol> RBRC05074 Flag-H2A.Z (H2afz) transgenic mice. H2A.Z gene is highly conserved across species and is essential for the viability of various organisms. No specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.) B6;B6D2-Tg(CAG-flag-H2A.Z) 戻し交配 系統名 (ブリーダー名) : C57BL/6 (日本SLC) B6;B6D2-Tg(CAG-flag-H2A.Z) 青木 不学 C (3-6 months) Developed by Nashun Buhe, Masashi Yukawa and Fugaku Aoki, Graduate School of Frontier Sciences, The University of Tokyo in 2009. Transgene was injected into the pronuclei of B6D2F1 fertilized eggs. true <A HREF="https://mus.brc.riken.jp/en/mouse_of_month/oct_2011_mm" target="_blank">Mouse of the Month Oct 2011</A> Flag-H2A. Z トランスジェニックマウス。H2A. Z (H2afz) はヒストン H2A の変異体であり、遺伝子発現の活性化に働くと考えられている。 東京大学大学院新領域創成科学研究科 青木不学先生、那順布和先生、湯川将之先生 (2009)B6D2F1の受精卵にマイクロインジェクションして作成。C57BL/6と交配を行い維持。 Fugaku AOKI Carrier x Noncarrier